Nikolaos Magiassis studied painting at The School of Fine Arts, Athens, under Dimitrios Geraniotis, Spyros Vikatos and Georgios Jakobides.

He painted portraits and still lifes in an academic manner, landscapes and seascapes in a more impressionistic language.

Nikolaos Magiassis exhibited his work in a number of solo and group exhibitions in Greece.

His works are found in many public and private collections, notably: The Koutlides Collection, The Averoff Gallery, The National Bank of Greece and The Piraeus Municipal Gallery.